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Category:
chemistry (312) biology (148)
Status:
Approved (435) Withdrawn (25)
Bio-Type:
Oncolytic virus (1) Vaccine (28) Blood extraction (7) Microbial extract (1) Recombinant enzyme (11) Recombinant polypeptide (1) Recombinant coagulation factor (9) Recombinant cytokines (13) Recombinant hormone (13) Recombinant glycoprotein (1) Bispecific antibody (1) Whole antibody (44) Fab fragment (6) ADC (3) Fusion protein (9)
Company:
Clovis Oncology (1) Covis Pharma (1) Cubist Pharmaceuticals (4) Daiichi Sankyo (9) Sumitomo Dainippon (3) Danco Lab (1) Dong-A Pharmaceutical (1) DUSA (1) Eisai (11) Endo (3) EndoCeutics (1) EUSA Pharma (1) Exelixis (1) Fera Pharms (1) Ferring Pharmaceuticals (1) Forest (6) Fresenius Kabi (1) Fujifilm group (1) Gedeon Richter (1) Genentech (17) Genzyme (12) Gilead (10) GlaxoSmithKline (32) Hanmi (1) Helsinn (1) Hospira (2) Hyperion Therapeutics (2) Immunomedics (1) Incyte (1) Intercept Pharmaceuticals (1) Ipsen (5) Ironwood (1) Janssen (23) Jazz Pharmaceuticals (1) Johnson & Johnson (10) Kyowa Hakko Kirin (6) Kythera (1) Lee's Pharm (1) Leo Pharma (1) Lexicon Pharmaceutical (1) LG Life Sciences (1) Ligand (2) Lilly (17) Lundbeck (4) Medicis Pharmaceutical (1) Medicure (1) MedImmune (3) Medivation (1) Melinta Therapeutics (1) Merck Serono (5) Merck Sharp & Dohme (27) MerLion Pharma (1) Merus Labs (1) Millennium Pharmaceutical (6) Mitsubishi Tanabe Pharma (8) Mylan Pharmaceutical (1) Neurocrine Biosciences (1) Nippon Shinyaku Pharma (2) Novartis (20) Novo Nordisk (4) Ono Pharmaceutical (2) Onxeo (1) Onyx Pharmaceutical (2) Organon (5) Orion (1) Otsuka (6) Paladin Pharma (1) Palatin Technologies (1) Perrigo (1) Pfizer (40) Pharmacyclics (1) Pierre Fabre Pharmaceutical (1) Portola Pharmaceutical (1) Procter & Gamble (1) Puma Biotechnology (1) Purdue Pharma (1) Rapidscan Pharma Solutions (1) Regeneron Pharmaceutical (5) Roche (9) Sanofi (25) Schwarz (1) Seattle Genetics (1) Shionogi (3) Shire (6) Sicor (1) Speciality European Pharma (1) Spectrum Pharmaceuticals (3) Sucampo (1) Sun Pharmaceutical (1) SOBI (3) Takeda (10) Teijin Pharma (1) Tesaro (2) Teva (6) The Medicines Company (3) Theravance Biopharma (1) Tibotec (2) UCB (7) Ucyclyd Pharma (1) United Therapeutics (1) Valeant (2) Vanda (2) Vansen (1) Vernalis (1) Vertex (3) ViiV Healthcare (6) Vistakon (1) Wakunaga (1) Warner chilcott (1) Wellstat Therapeutics (1) XenoPort (1) Yakult (1) Zydus cadila (1) Unknown (2) Barr Labs (1) Kedrion (1) FFF Enterprises (1) Bio Products Laboratory (1) Aptevo (1) University of Queensland (1) BioSpecifics (1) PaxVax (1) SK Chemicals (1) Protein Sciences Corporation (2) Marathon Pharmaceuticals (1) Relypsa (1) Affymax (1) Kastle (1) Sanofi Pasteur MSD (1) Alkermes Pharma (1) Zai Lab (1) Synergy Pharmaceuticals (1) Sprout Pharmaceuticals (1) Alfresa Pharma (1) Romark Laboratories (1) ThromboGenics (1) Protalix Biotherapeutics (1) Dyax Pharma (1) Insmed (1) Biogen (9) Inspiration Biopharmaceuticals (1) Emergent (2) Octapharma (1) Hikma (1) Sarepta Therapuetics (1) Radius Health (1) Blue Earth (1) Baxalta (6) Ivax (1) MannKind Corporation (1) Sandoz (1) CSL Behring (2) Elusys Therapeutics (1) Ionis Pharmaceuticals (2) CSL (4) Jiliya (Hangzhou) Pharmaceutical (1) 3M (1) Abbott (6) Abbvie (11) Acadia Pharmaceuticals (1) Acorda Therapeutics (1) Actavis (3) Actelion (3) Aegerion (1) Agouron Pharmaceuticals (1) Alcon (6) Alexion (1) Allergan (4) Almirall (3) Altana (1) Amgen (11) Amneal (1) Anacor Pharmaceuticals (2) Arbor Pharmaceuticals (1) Arena Pharmaceuticals (1) Ariad Pharmaceuticals (2) Asahi Kasei (1) Astellas (12) AstraZeneca (10) Basilea Pharmaceutica (1) Bausch & Lomb (2) Baxter (1) Bayer (9) BioMarin Pharmaceutical (3) Boehringer Ingelheim (13) Bristol-Myers Squibb (14) Cangene Corporation (3) Celgene (7) Chiesi (1) Chugai (10) Clinigen (1)
Indication:
Meningitis (1) Acne (1) Actinic keratosis (AK) (3) Acute bacterial exacerbation of chronic obstructive pulmonary disease (1) Acute bacterial skin and skin structure infections (ABSSSI) (5) Acute coronary syndrome (ACS) (3) Acute lymphoblastic leukaemia (ALL) (5) Acute myeloid Leukemia (AML) (4) Acute otitis externa (AOE) (1) Acute promyelocytic leukemia (APL) (1) Acute rejection in renal transplantation (1) Adjunct treatment for epilepsy (1) Adjuncts to anesthesia (1) Advanced breast cancer (1) Advanced prostate cancer (2) Advanced renal cell carcinoma (RCC) (4) AIDS-related Kaposi’s sarcoma (1) Alcohol dependence (1) Allergic conjunctivitis (3) Allergic rhinitis (AR) (2) Alzheimer's disease (AD) (1) Amyotrophic lateral sclerosis (ALS) (1) Anaesthetic (4) Anemia (2) Angina pectoris (1) Anxiety (2) Appendicitis (1) Arrhythmia (1) Arthritis (1) Aspergillosis (1) Asthma (3) Atopic dermatitis (2) Atrial fibrillation (4) Atrial flutter (3) Attention deficit hyperactivity disorder (ADHD) (2) Basal cell carcinoma (BCC) (3) BCG-refractory carcinoma in situ of the urinary bladder (3) Benign prostatic hypertrophy (2) Bipolar I disorder (5) Bipolar mania (1) Bladder cancer (1) Bone marrow cancer (1) BRAF mutant melanoma (2) Breast cancer (9) Bronchial asthma (1) Candidiasis (2) Carcinoid syndrome (1) Cardiovascular risk reduction (1) Hyperkalaemia (2) CD20-positive follicular lymphoma (1) Precocious puberty in children (1) Chemotherapy-induced nausea and vomiting (3) Chronic angina (1) Apnoea (1) Chronic constipation (1) Chronic idiopathic constipation (CIC) (3) Chronic idiopathic urticaria (CIU) (1) Chronic immune thrombocytopenia (1) Chronic iron overload (1) Chronic lymphocytic leukemia (CLL) (6) Mucocutaneous lymph node syndrome (Kawasaki syndrome) (1) Chronic myeloid leukemia (CML ) (7) Chronic obstructive pulmonary disease (COPD) (1) Chronic thromboembolic pulmonary hypertension (CTEPH) (1) Soft tissue disorders (1) Chronic urticaria (1) Clostridium difficile infection (1) Clostridium difficile-associated diarrhea (CDAD) (2) Cytomegalovirus (CMV) retinitis (2) Cold sore infections (1) Colorectal disorder (1) Giardia lamblia disease (1) Community-acquired pneumonia (CAP) (3) Congestive heart failure (1) Conscious sedation (1) Contrast agents (1) Coronary artery disease (CAD) (1) Crohn's disease (6) Cryptococcus neoformans (1) Cutaneous T cell lymphoma (CTCL) (3) Cystic fibrosis (CF) (2) Neuronal ceroid lipofuscinoses (1) Cytoprotective adjuvant (1) Anaplastic lymphoma kinase (ALK)-positive NSCLC (1) ROS1-positive non-small cell lung cancer(NSCLC) (1) Deep vein thrombosis (DVT) (1) Cholera (1) Dementia (1) Depression (3) Diabetic macular edema (1) Diabetic nephropathy (1) Herpes simplex virus (2) Diarrhea (1) Irritable bowel syndrome with diarrhea (IBS-D) (3) Differentiated thyroid cancer (1) Tumor necrosis factor receptor associated periodic syndrome (1) Hyperimmunoglobulin D syndrome (1) Familial mediterranean fever (1) Dry eye disease (1) Hepatic encephalopathy (1) Duchenne muscular dystrophy (DMD) (2) Duodenal ulcer (2) Dyslipidemia (1) Dysmenorrhea (1) Dyspareunia-pain during sex (2) Dyspepsia (1) Irritability associated with pediatric autism spectrum disorder (1) Transplant rejection (2) Epilepsy/Seizures (2) Erectile dysfunction (ED) (2) Erosion and ulceration (1) Erosive esophagitis (EE) (2) Eye disorders (2) Erythema nodosum leprosum (ENL) (1) Anal cancer (2) Vulvovaginal cancer (2) Essential hypertension-重复 (1) Essential thrombocythaemia (ET) (1) Excessive sleepiness (1) Analgesia induction and maintenance (1) Familial chylomicronemia syndrome (FCS) (1) Fibromyalgia (FM) (1) Follicular B cell non-Hodgkin lymphoma (FL) (1) Follicular lymphoma (2) Gastric cancer (3) Gastric ulcer (1) Gastroesophageal reflux disease (GERD) (3) Gastrointestinal stromal tumors (GISTs) (4) Gaucher's disease (GD) (4) Generalised anxiety disorder (GAD) (2) Generalized tonic-clonic status epilepticus (GTCSE) (1) Germline BRCA mutated advanced ovarian cancer (1) Glaucoma (2) Induced mydriasis (1) Growth hormone deficit (5) HBV infection (10) HCV infection (7) Heart failure (2) Respiratory disease caused by adenovirus type 4 and type 7 (1) Hematopoietic stem cell transplantation (HSCT) (1) Restoration and maintenance of circulating blood volume (1) Pediatric plaque psoriasis (1) Herpes zoster keratitis (2) Hypovolemia (1) Hypoalbuminemia (1) Ovarian hyperstimulation syndrome (OHSS) (1) Adult respiratory distress syndrome (ADRS) (1) Cardiopulmonary bypass (1) HIV infection (22) Hormone refractory prostate cancer (1) HSV infection (2) Huntington's disease (2) Hyperammonaemia (1) Hypercalcemia (2) Hypercholesterolemia (6) Hyperlipidemia (1) Hypertension (12) Hyperuricemia (1) Hypogonadotropic hypogonadism (1) Hyponatremia (2) Idiopathic pulmonary fibrosis (IPF) (1) Idiopathic thrombocytopenic purpura (ITP) (2) Ileus (1) Impetigo (1) Influenza virus infection (1) Insomnia (2) Invasive aspergillosis (2) Hepatitis A viral infection (2) Invasive mucormycosis (1) Irritable bowel syndrome with constipation (IBS-C) (2) Juvenile rheumatoid arthritis (JRA) (5) Leiomyoma (1) Leukemia (1) Localized submental fat (1) Lung cancer (1) Lymphoma (2) Macular degeneration (1) Major depressive disorder (MDD) (9) Malignancies (1) Mania (2) Mantle cell lymphoma (MCL) (5) Medullary thyroid cancer (MTC) (2) Melanoma (7) Metastatic breast cancer (4) Metastatic castration-resistant prostate cancer (mCRPC) (2) Metastatic colorectal cancer (CRC) (5) Metastatic gastric carcinoma (2) Metastatic melanoma (3) Methanol poisoning (1) Migraine (1) Mixed dyslipidemia (1) Moderate-to-severe acute pain (1) Monitored anesthesia care (MAC) (1) Multiple myeloma (MM) (11) Multiple sclerosis (MS) (10) Muscle relaxant (1) Myelodysplastic syndrome (MDS) (3) Myelofibrosis (1) Myocardial infarction (MI) (5) Myocardial perfusion imaging (MPI) (1) Nausea and vomiting (1) Non small cell lung cancer (NSCLC) (10) Non-24-hour sleep-wake disorder (N24HSWD) (1) Non-Hodgkin B-cell lymphomas (3) Non-Hodgkin’s lymphoma (NHL) (4) Non-small cell lung cancer associated anorexia or cachexia (1) Non-ST elevation acute coronary syndrome (NSTE-ACS) (2) NSAID-associated gastric ulcer (1) Obesity (2) Ocular hypertension (6) Onychomycosis (1) Open-angle glaucoma (6) Opioid induced constipation (OIC) (3) Osteoarthritis (OA) (2) chronic low back pain (1) Osteoporosis (2) Ovarian cancer (4) Overactive bladder (OAB) (2) Ovulation induction (1) Paget's disease (1) Pancreatic cancer (1) Parkinson's disease (PD) (2) Partial seizures (1) Peptic ulcer (1) Percutaneous coronary intervention (PCI) (3) Percutaneous transluminal coronary angioplasty (PTCA) (1) Peripheral arterial disease (PAD) (2) Peripheral T cell lymphoma (PTCL) (4) Pneumonia (1) Postherpetic neuralgia (PHN) (1) Postmenopausal osteoporosis (4) Postmyocardial Infarction Syndrome (1) Prader-Willi syndrome (1) Premature LH surges (2) Primary biliary cirrhosis (PBC) (1) Primary hypercholesterolemia (3) Kidney disorders (1) Primary hypertension (2) Primary hypogonadism (1) Diphtheria (6) Haemophilus infection (5) Pertussis (6) Prostate cancer (6) Poliomyelitis (4) Tetanus (6) Psoriasis (5) Psoriatic arthritis (10) Pulmonary arterial hypertension (5) Pulmonary embolism (1) Dupuytren's contracture (1) Rejection of organ transplantation (4) Peyronie's disease (1) Renal cell carcinoma (6) Botulism (1) Restless legs syndrome (2) Rheumatoid arthritis (RA) (14) Varicella zoster virus infections (1) Schizophrenia (11) Seasonal allergic rhinitis (1) Secondary hyperparathyroidism (HPT) (2) Sedation (1) Sjoegren's syndrome (1) Skin infectious (1) Sleep initiation and maintenance disorders (1) Small cell lung cancer (SCLC) (2) Small lymphocytic lymphoma (SLL) (2) Smoking cessation (1) Soft tissue infections (3) Soft tissue sarcoma (2) Solid tumours (2) Superficial basal cell carcinoma (sBCC) (1) Superficial punctate keratitis (1) Tardive dyskinesia (1) T-cell acute lymphoblastic leukemia (T-ALL) (1) Thrombocytopenia (4) Thrombotic cardiovascular events (TCE) (2) Thyroid cancer (2) Tuberculosis (3) Type 2 diabetes (12) Ulcerative colitis (5) Urea cycle disorders (UCDs) (2) Urinary frequency (1) Urinary incontinence (1) Urinary urgency (1) Urticaria (2) Uveitis (3) Venous thromboembolism (VTE) (1) Ventilator-associated pneumonia (1) Vulvovaginal atrophy (2) Zollinger-Ellison syndrome (2) Head and neck cancer (3) Bone cancer (1) Nasopharyngeal cancer (1) Genital warts (2) Influenza A virus infections (6) Polycythaemia vera (1) Hodgkin lymphoma (1) Systemic anaplastic large cell lymphoma (1) Inhalational anthrax (2) Cardiac ischemic complications (2) Colorectal cancer (4) Cryopyrin-Associated Periodic Syndromes (CAPS) (2) Systemic juvenile idiopathic arthritis (1) Respiratory depression (1) Prophylaxis of organ rejection (2) Vulvar intraepithelial neoplasia (1) Rejection of renal transplantation (3) Rejection of liver transplantation (1) Rejection of lung transplantation (1) Herpes labialis (1) Influenza B virus infection (2) Genital herpes (1) Rejection of pancreatic transplantation (1) Primary peritoneal cancer (1) Fallopian tube cancer (1) Epithelial ovarian cancer (1) Ankylosing Spondylitis (AS) (8) Primary dysmenorrhea (PD) (1) Familial adenomatous polyposis (FAP) (1) Iritis (1) Cyclitis (1) Life- or limb-threatening infections caused by susceptible strains (2) Acute pain (AP) (2) Low back pain (1) Shoulder periarthritis (1) Tendonitis (1) Cervico-omo-brachial syndrome (1) After surgery, post-traumatic and anti-inflammatory (1) Fungal infection (1) Postoperative inflammation and pain following ocular surgery (1) Candidemia (1) Nosocomial Pneumonia (NP) (2) Osteoporosis in men (1) Glucocorticoid-induced osteoporosis (1) Ethylene glycol poisoning (1) Marginal zone lymphoma (1) Meningococcal infection (1) Hyperlipoproteinaemia type IIa (1) Myeloproliferative Disorders (MPD) (2) Aggressive systemic mastocytosis (ASM) (2) Hypereosinophilic syndrome (HES) (1) Dermatofibrosarcoma protuberans (DFSP) (1) Chronic eosinophilic leukemia (CEL) (1) Chronic kidney disease (2) Colon cancer (2) Complicated skin and skin structure infections (cSSSI) (3) Cirrhosis (1) Dermatitis (1) Autosomal dominant polycystic kidney disease (ADPKD) (1) Transfusion-related iron overload (1) Microscopic polyangiitis (1) Granulomatosis with polyangiitis (1) Spondyloarthritis (3) Susceptible bacterial infections (1) Atypical hemolytic uremic syndrome (AHUS) (1) Paroxysmal Nocturnal Hemoglobinuria (PNH) (1) Systemic mastocytosis with associated hematological neoplasm (1) Mast cell leukemia (1) Chronic heart failure (1) Acute angina (1) Primary humoral immunodeficiency (1) Familial hypercholesterolemia (2) Anthrax (2) Neuroblastoma (1) Heterozygous familial hypercholesterolemia (1) Muckle-Wells Syndrome (MWS) (1) Staphylococcus aureus bloodstream infections (2) T-cell lymphoblastic lymphoma (1) Multicentric Castleman’s Disease (MCD) (1) Hypervolemic hyponatremia (1) Bacterial conjunctivitis (1) Syndrome of inappropriate antidiuretic hormone secretion (SIADH) (1) Accelerate gastrointestinal recovery following surgeries (2) Pain (3) Acute pain (1) Stroke (2) Schizoaffective Disorder (1) Unstable angina (2) Non-ST segment elevation myocardial infarction (NSTEMI) (2) ST-segment elevation myocardial infarction (STEMI) (2) Metastatic non-small cell lung cancer (4) Diabetic peripheral neuropathic pain (DPNP) (1) Chronic musculoskeletal pain (1) Uncomplicated skin and skin structure infections (1) Enterococcus faecium infections (1) Methicillin-resistant staphylococcus aureus infections (1) Organ transplant删除 (1) Prevention of postmenopausal osteoporosis (1) Bone pain (1) Hepatic impairment (1) Symptomatic spontaneous superficial-vein thrombosis of the lower limbs (1) Acute pulmonary thromboembolism (1) Facial Erythema of Rosacea (1) Tic disorders (1) Irritability (1) Autistic disorder (1) Bipolar disorder (2) Dementia with Lewy bodies (1) Primary hyperlipidemia (4) Mixed hyperlipidemia (2) Homozygous familial hypercholesterolemia (3) Homozygous sitosterolemia (1) Diabetic peripheral neuropathy (DPN) (1) Anesthesia (2) Skeletal muscle relaxation (1) Urothelial cancer (3) Relapsed or refractory malignant lymphoma (1) Idiopathic Parkinson's disease (1) Recurrence suppression after ischemic cerebrovascular disorder (1) Stable angina (1) Old myocardial infarction (1) External genital and perianal warts (1) Recent myocardial infarction (1) Cervical carcinoma (3) Pancreatic neuroendocrine tumors (pNET) (1) Waldenström's macroglobulinemia (WM) (1) Lower respiratory tract disease caused by RSV (1) Macular edema (1) Diabetes (5) Diagnostic agents (4) Behcet's disease (1) Gastroesophageal junction adenocarcinoma (2) Pediatric Crohn’s disease (2) Pediatric ulcerative colitis (1) HER2-positive metastatic breast cancer (3) Familial cold autoinflammatory syndrome (1) Hidradenitis suppurativa (2) Type 1 diabetes (2) Hemophilia A (7) Hemophilia B (2) Neutropenia (3) Hairy cell leukemia (2) Condylomata acuminata (2) Kaposi's sarcoma (1) Renal carcinoma (4) Acute ischemic stroke (AIS) (1) Acute myocardial infarction (AMI) (2) Acute massive pulmonary embolism (1) Contraception (1) Hypoactive sexual desire disorder (HSDD) (1) Mucopolysaccharidosis VI (Maroteaux-Lamy syndrome) (1) Mucopolysaccharidosis II (Hunter syndrome) (1) Mucopolysaccharidosis I (1) Diarrhea caused by giardia or cryptosporidium (1) Cataplexy in narcolepsy (1) Excessive daytime sleepiness (EDS) in narcolepsy (1) Symptomatic vitreomacular adhesion (1) Spinal muscular atrophy (1) Hyperphosphatemia (1) Lower extremity diabetic neuropathic ulcers (1) Infertility (1) Growth failure (7) Turner syndrome (4) Small for gestational age (SGA) (3) Noonan Syndrome (1) Idiopathic short stature (3) SHOX deficiency (1) Oral mucositis (1) Sepsis (1) Allogeneic RBC transfusion (1) Gram-positive bacterial infection (3) Hypoglycemia (2) Peritoneum cancer (1) Hereditary orotic aciduria (1) Pruritus (1) Retinal vein occlusion (1) Terminate pregnancy (1) Merkel cell carcinoma (1) RSV infection (1) Liposarcoma (1) Advanced melanoma (1) Plaque psoriasis (6) Bleeding (1) Emergency surgery (1) Gout (1) Burns (2) Interstitial cystitis (1) Metastatic squamous non-small cell lung cancer (NSCLC) (2) Bacterial infection (4) Von Willebrand disease (1) Chemotherapy induced poisoning (1) Thromboembolism (1) Infectious disease (3) Skin disorders (1) Human papillomavirus infections (HPV) (2) AIDS-related chronic diarrhea (1) Allergic diseases (1) Choroidal neovascularisation (1) Hallucinations and delusions associated with Parkinson's disease psychosis (1) Pustular psoriasis (2) Psoriatic erythroderma (2) Psoriasis vulgaris (2) Juvenile idiopathic arthritis (JIA) (5) Immune thrombocytopenic purpura (1) Hirsutism (1)
Aprv. Year:
1995 (49) 1996 (25) 1997 (25) 1998 (25) 1999 (17) 2000 (15) 2001 (12) 2002 (14) 2003 (15) 2004 (9) 2005 (12) 2006 (18) 2007 (13) 2008 (19) 2009 (20) 2010 (9) 2011 (18) 2012 (23) 2013 (21) 2014 (27) 2015 (30) 2016 (22) 2017 (22)
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