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Category:
chemistry (301) biology (54)
Status:
Approved (81) Withdrawn (4) NDA Filing (10) BLA Filing (1) Phase Ⅲ (38) Phase Ⅱ (124) Phase Ⅰ (96) IND Filing (1)
Clinical Stage:
Pending (25) Active (110) Discontinued (135)
Bio-Type:
CAR T cell therapy (5) Vaccine (4) Allergen extract (1) Microbial extract (1) Recombinant enzyme (2) Recombinant cytokines (1) Recombinant hormone (1) Bispecific antibody (4) Single-chain FV antibody fragment (scFv) (1) Whole antibody (21) ADC (5) Single-domain antibody (Nanobody) (1) Fusion protein (1)
Indication:
Acute bacterial skin and skin structure infections (ABSSSI) (2) Acute lymphoblastic leukaemia (ALL) (2) Acute myeloid Leukemia (AML) (7) Acute otitis externa (AOE) (1) Acute pyelonephritis (AP) (1) Adjuncts to anesthesia (1) Advanced prostate cancer (1) Alcohol dependence (1) Allergic conjunctivitis (3) Allergic rhinitis (AR) (3) Alzheimer's disease (AD) (6) Anaesthetic (2) Anemia (2) Angina pectoris (2) Anxiety (2) Arrhythmia (2) Asthma (8) Atherosclerosis (1) Atopic dermatitis (1) Atrial fibrillation (1) Atrial flutter (1) Attention deficit hyperactivity disorder (ADHD) (8) Benign prostatic hypertrophy (2) Bipolar mania (1) Bladder cancer (1) BRCA-deficient breast cancer (1) Breast cancer (6) Candidiasis (1) Hypothyroidism (1) Cerebral vasospasm (1) Chemotherapy-induced nausea and vomiting (1) Anorexia (1) Chronic lymphocytic leukemia (CLL) (6) Chronic myeloid leukemia (CML ) (2) Chronic obstructive pulmonary disease (COPD) (1) Clostridium difficile infection (1) Cognitive disorders (4) Community-acquired pneumonia (CAP) (2) Complicated urinary tract infection (1) Congestive heart failure (1) Constipation (2) Crohn's disease (5) Cutaneous T cell lymphoma (CTCL) (1) Cystic fibrosis (CF) (3) Deep vein thrombosis (DVT) (1) Depression (3) Diabetic macular edema (1) Diabetic nephropathy (3) Diabetic neuropathic pain (DNP) (2) Irritable bowel syndrome with diarrhea (IBS-D) (1) Dry eye disease (1) Duodenal ulcer (1) Dyslipidemia (1) Dyspepsia (1) Endometrial cancer (1) Rheumatic disorders (2) Endometriosis (1) Epilepsy/Seizures (5) Erectile dysfunction (ED) (3) Erythema nodosum leprosum (ENL) (1) Urogenital cancer (1) Essential hypertension-重复 (1) Analgesia induction and maintenance (1) Follicular lymphoma (1) Friedreich's ataxia (1) Gastroesophageal reflux disease (GERD) (2) Gastrointestinal stromal tumors (GISTs) (1) Gaucher's disease (GD) (1) Digital ulcers (1) Glaucoma (5) Gram-positive and Gram-negative bacterial infections (1) Wet age-related macular degeneration (1) HCV infection (6) Heart failure (6) Hematopoietic stem cell transplantation (HSCT) (1) HIV infection (7) HSV infection (1) Timothy grass pollen-induced allergic rhinitis (1) Hypercholesterolemia (4) Hyperlipidemia (1) Hypertension (16) Hypertriglyceridemia (1) Hypogonadotropic hypogonadism (1) Idiopathic pulmonary fibrosis (IPF) (1) Inflammatory bowel disease (1) Influenza virus infection (3) Insomnia (4) Irritable bowel syndrome (IBS) (1) Juvenile rheumatoid arthritis (JRA) (1) Leiomyoma (1) Thromboangiitis obliterans (1) Leukemia (2) Lymphoma (3) Macular degeneration (1) Major depressive disorder (MDD) (3) Mania (1) Mantle cell lymphoma (MCL) (2) Renal osteodystrophy (1) Melanoma (4) Migraine (2) Multiple myeloma (MM) (13) Multiple sclerosis (MS) (6) Muscle relaxant (1) Myelodysplastic syndrome (MDS) (6) Neuropathic pain (3) Niemann-Pick diseases (1) Non small cell lung cancer (NSCLC) (10) Non-Hodgkin B-cell lymphomas (2) Non-Hodgkin’s lymphoma (NHL) (5) NSAID-associated gastric ulcer (1) Obesity (3) Ocular hypertension (5) Open-angle glaucoma (4) Osteoarthritis (OA) (2) Osteogenesis imperfecta (1) Ovarian cancer (5) Overactive bladder (OAB) (1) Paget's disease (1) Pancreatic cancer (3) Parkinson's disease (PD) (5) Partial seizures (2) Peptic ulcer (2) Peripheral T cell lymphoma (PTCL) (2) Lipid metabolism disorders (1) Pneumonia (1) Thrombosis (1) Primary biliary cirrhosis (PBC) (1) Primary hypercholesterolemia (1) Primary hypertension (1) Primary hypogonadism (1) Prostate cancer (7) Psoriasis (5) Psoriatic arthritis (4) Pulmonary arterial hypertension (8) Dupuytren's contracture (1) Rejection of organ transplantation (1) Peyronie's disease (1) Renal cell carcinoma (2) Respiratory tract infection (1) Rheumatoid arthritis (RA) (8) Schizophrenia (12) Seasonal allergic rhinitis (1) Secondary hyperparathyroidism (HPT) (1) Skin infectious (1) Small cell lung cancer (SCLC) (3) Small lymphocytic lymphoma (SLL) (1) Soft tissue infections (1) Solid tumours (32) Systemic lupus erythematosus (4) Thrombotic cardiovascular events (TCE) (1) Metabolic disorders (1) Tourette's syndrome (1) Triple negative breast cancer (1) Type 2 diabetes (3) Ulcerative colitis (3) Urinary incontinence (2) Urticaria (2) Uterine fibroids (1) Uveitis (3) Zollinger-Ellison syndrome (1) Fabry disease (1) Hodgkin lymphoma (1) Colorectal cancer (2) Pain and inflammation associated with cataract surgery (1) Postoperative macular oedema associated with cataract surgery (1) Ankylosing Spondylitis (AS) (2) Helicobacter pylori infection (1) Pulmonary arterial hypertension secondary to scleroderma (1) Fungal infection (1) Nosocomial Pneumonia (NP) (1) Marginal zone lymphoma (1) Neonatal respiratory distress syndrome (1) Chronic kidney disease (1) Colon cancer (1) Muscle hypertonia (1) Dermatitis (1) Cholangiocarcinoma (1) Spondyloarthritis (1) Age-related macular degeneration (AMD) (3) Pain (9) Stroke (2) Bipolar disorder (3) Homozygous familial hypercholesterolemia (1) Anesthesia (4) Skeletal muscle relaxation (1) Urothelial cancer (1) Waldenström's macroglobulinemia (WM) (1) Lower respiratory tract disease caused by RSV (1) B-cell lymphoma (1) Diabetes (1) Pediatric Crohn’s disease (1) Malaria (1) Sickle cell disease (1) Hidradenitis suppurativa (1) Condylomata acuminata (1) Renal carcinoma (1) Acute myocardial infarction (AMI) (1) Hematological cancer (3) Symptomatic vitreomacular adhesion (1) Eosinophilic esophagitis (EoE) (1) Immune-inflammatory diseases (2) Autoimmune diseases (1) Acute heart failure (1) Sepsis (1) Septic shock (2) Preterm labor (1) Peritoneum cancer (2) Gram-negative bacterial infection (1) Progressive supranuclear palsy (1) Staphylococcal infection (1) Brain injury (2) Glioblastoma (2) Glioma (2) Hepatic fibrosis (1) Graft versus host disease (3) Substance abuse and dependence (1) Plaque psoriasis (4) Lupus nephritis (1) Allergic asthma (1) Thrombosis (3) Panic disorder (1) HRV infection (1) Systemic sclerosis (2) Respiratory syncytial virus infection (2) Raynaud's phenomenon (1) Mesothelioma (1) Gastrointestinal disorders (2) Cutaneous lupus erythematosus (1) Pulmonary fibrosis (1) Brain cancer (1) Lipodystrophy (1) Bacterial infection (3) Cocaine abuse (1) Celiac disease (1) Acute kidney injury (1) Diabetic neuropathy (1) Thelassemia (2) Ocular pain (1) Musculoskeletal pain (1) Vascular calcification (1) Discoid lupus erythematosus (1) Postoperative inflammation (1) Renal failure (1) Arterial occlusive disease (1) Psychiatric disorders (4) Coronary restenosis (1) Infectious disease (1) Neurological disease (3) hematological malignancies (2) Central nervous system disorders (1) Ventricular tachycardia (1) Cardiovascular disorders (5) Skin disorders (1) Inflammation (6) Myocardia ischemia (2) Hallucinations and delusions associated with Parkinson's disease psychosis (1) Juvenile idiopathic arthritis (JIA) (1) Immune thrombocytopenic purpura (1) Ocular inflammation (1)
Country:
US (43) JP (2) EU (6) CH (1) IT (1) AU (1) DK (1)
Aprv. Year:
 (1) 1995 (3) 1996 (6) 1997 (4) 1998 (4) 2000 (3) 2001 (3) 2002 (4) 2005 (2) 2006 (1) 2007 (1) 2008 (1) 2009 (3) 2010 (3) 2012 (2) 2013 (4) 2014 (3) 2015 (4) 2016 (3) 2017 (2)
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